Hematlas for macOS

Ask the literature.
Get a brief you can defend.

Ask a hematology question the way you’d actually say it. Hematlas reads the primary literature and returns a sourced brief — every sentence linked to the exact paper, every number to a verbatim quote you can hover and read. Sources only; it never invents.

Download for MacFree · Requires macOS 26 · Apple siliconiPhone companionTestFlight beta — soon

Grounded in PubMed · PubMed Central · ClinicalTrials.gov · Cochrane · ASH · ASTCT

Hematlas on macOS: a hematology question answered with a fully-sourced evidence brief
The difference

The relative risk of death from bleeding was 0.99.1

A number you could act on — so you should be able to see exactly where it came from.

PubMed · [1]High
Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial
We found that tranexamic acid did not reduce death from gastrointestinal bleeding.
Death due to bleeding: RR 0.99 · 95% CI 0.82–1.18
HALT-IT Trial Collaborators · 2020 · The Lancet
Search-first toolsten blue links and a login wall.
AI answer boxesa fluent paragraph you can’t check.
Hematlasa brief where every sentence shows its source.

Verbatim, not paraphrased — every quote re-checked against the source text.

A claim it can’t ground is removed, not guessed.

Open the paper in one click.

We didn’t build a smarter search box. We built the brief you’d want to defend.

Proof, not adjectives

Pick a sentence. See the source.

The same gesture, anywhere in hematology — a claim, then the exact paper sentence behind it. Four examples, four source types.

PubMed · The Lancet

Tranexamic acid did not reduce mortality in acute gastrointestinal bleeding.1

We found that tranexamic acid did not reduce death from gastrointestinal bleeding.

ASTCT · Biol Blood Marrow Transplant

Cytokine release syndrome must include fever at onset and may progress to hypotension and hypoxia.2

Symptoms can be progressive, must include fever at the onset and may include hypotension, capillary leak (hypoxia) and end organ dysfunction.

ASH · Blood Advances

Corticosteroids are recommended over observation for newly diagnosed adults with ITP and platelets below 30×10⁹/L.3

In adults with newly diagnosed ITP and a platelet count of <30 × 10⁹/L who are asymptomatic or have minor mucocutaneous bleeding, the American Society of Hematology (ASH) guideline panel suggests corticosteroids rather than management with observation.

NEJM · MSH trial

Hydroxyurea reduced the annual rate of painful crises in adults with sickle cell anemia.4

The 152 patients assigned to hydroxyurea treatment had lower annual rates of crises than the 147 patients given placebo (median, 2.5 vs. 4.5 crises per year, P<0.001).

Four sentences. Four receipts. Multiply that by a whole brief.

It never invents

It only knows
what it can cite.

No web guessing. No training-memory hunches. If the literature doesn’t answer, it says so — and shows you the gap instead of filling it with a guess.

PubMed / PMCPeer-reviewed literature & open-access full text
ClinicalTrials.govRegistered trials, outcomes & status
CochraneSystematic reviews & meta-analyses
ASH · ASTCTSociety guidelines & consensus statements
The grounding loop
fetch sourcecache the exact textrecheck every quote (≥ 0.92 match)drop what won’t ground
Open questions
  • Whether any GI-bleed subgroup benefits from early TXA remains unresolved.
  • Optimal timing of tocilizumab vs corticosteroids in grade-2 CRS is debated.

We’d rather show you the gap than fill it with a guess.

Not one zip code

The same question has a different answer in a different hospital.

First-line management

Endoscopic haemostasis within 24 hours with proton-pump-inhibitor infusion; transfuse to a restrictive haemoglobin threshold of 7 g/dL.2

GlobalSub-Saharan AfricaSouth AsiaLatin America

A US-centric tool gives one answer. Hematlas marks resource tiers — and tells you plainly when the evidence was generated somewhere your patient doesn’t live.

Set like a journal

Forest plots, GRADE tables, decision trees — rendered, not just described.

Hairlines, not chartjunk. Even the figure data carries its own citation.

Forest plot rendered in Hematlas: all-cause mortality for tranexamic acid vs placebo across four trials
Actual output — a forest plot drawn from four trials in one brief. Each row traces to its source.
Certainty of evidence (GRADE)
OutcomeEffectCertainty
Death from bleedingNo reduction
Venous thromboembolismIncreased
RebleedingNo clear benefit
Acute GI bleed — first hour
Acute GI bleed
Resuscitate & risk-assess
Endoscopy < 24 h
VaricealBand ligation + vasoactive drug
Non-varicealPPI + endoscopic haemostasis
A Hematlas evidence brief rendered natively in its own macOS window
In your Dockyet another AI tab ×
Native, quiet, yours

It lives in your Dock, not a browser tab.

Summon it from anywhereA keystroke, like Spotlight — your question, answered without leaving what you’re doing.
Works offlineBriefs render and reopen with no network. Nothing about your patients leaves the Mac.
Built in Liquid GlassReal macOS materials, real type, a real keyboard. Not a website in a frame.
Download for MacFree · Requires macOS 26 · Apple silicon iPhone companionTestFlight beta — soon

Web tools forget you the moment you close the tab. Hematlas keeps your notebook.

Ask the literature.
Get a brief you can defend.

Download for MacFree · Requires macOS 26 · Apple siliconiPhone companionTestFlight beta — soon

Grounded in  PubMed · PMC · ClinicalTrials.gov · Cochrane · ASH · ASTCT


Every claim links to a primary source · Hematlas is a research aid, not medical advice.

Set in New York & SF Mono.